发明名称 PREPARATION OF 2-METHYL-3-HYDROXY-4-ETHYLAMINOMETHYL-5-METHYLMERCAPTOMETHYL- DINE AND ITS ACID ADDITION SALTS
摘要 <p>2-Methyl-3-hydroxy-4-ethylaminomethyl-5-methylmercapto-methyl-pyridine and its acid addition salts are produced by a novel process involving treating a pyridine derivative of the general formula wherein R is -CH=N-CH2- or -CH2-N=CH-, or a salt thereof, with sodium borohydride, with zinc and an acid, or with hydrogen in the presence of Raney nickel. This novel process provides the compounds in very high yields and in excellent purity.</p>
申请公布号 CA1068710(A) 申请公布日期 1979.12.24
申请号 CA19750236795 申请日期 1975.10.01
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG 发明人 SAIKO, OTTO
分类号 B01J25/00;C07D213/66;(IPC1-7):07D213/66 主分类号 B01J25/00
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