发明名称 |
TCL-1 gene and protein and related methods and compositions |
摘要 |
The present invention relates to nucleotide sequences of TCL-1 genes and amino acid sequences of their encoded proteins, as well as derivatives and analogs thereof, and antibodies thereto. The TCL-1 gene sequence is preferentially expressed early in T and B lymphocyte differentiation. The present invention further relates to the use of TCL-1 genes and their encoded proteins as diagnostic and therapeutic reagents for the detection and treatment of disease states associated with chromosomal abnormalities.
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申请公布号 |
US5985598(A) |
申请公布日期 |
1999.11.16 |
申请号 |
US19940330272 |
申请日期 |
1994.10.27 |
申请人 |
THOMAS JEFFERSON UNIVERSITY;RAGGIO-ITALGENE S.P.A. |
发明人 |
RUSSO, GIANDOMENICO;CROCE, CARLO M. |
分类号 |
A61K38/00;C07K14/47;C12Q1/68;(IPC1-7):C12P21/02;C07H21/04;C12N15/12;C12N15/85 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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