| 摘要 |
<p>New glucosamin silyl compounds of formula: (FORMULA) wherein X is a carbonyl group, R1, R4 and R6 a tri-alkyl-lower-sylil group, in particular trimethyl-silyl, R2 is an alkyl group eventually substituted or an aryl carbocylic group, R3 is hydrogen or an alkyl group, R7 and R13 is hydrogen or lower are alkyl, R8 is hydrogen, lower alkyl, lower hydroxy-alkyl free or with modified function, lower mercapto-alkly free or with modified function, lower halogeno-alkyl, cycloi-alkyl comprising 5 or 6 carbon atoms, lower cycloalky-alkyl, of which the cycloalkyl part comprises 5 or 6 carbon atoms, an aryl group eventually substituted or aralkyl, a nitrogenous heterocyclyl rest or lower heterocyclyl-alkyl, R7 and R8 have in common a rest of alkylen having 3 or 4 carbon atoms, R9 is hydrogen or a lower alkyl group and the rest r10, R11, R12 are, independently from each other, a carboxyl rest eventually esterified or amidated and R11 may be hydrogen. The preparation process of these new compounds, as well as the pharmaceutical preparations thereof are disclosed. The preparations may be used as immunizing means. </p> |
