摘要 |
A synthetic substrate having the structure R1 - Pro - X - Y - NH - R2, wherein R1 is a blocking group, -NH-R2 is a chromogenic or fluorescent group, X represents a phenylalanyl, beta -cyclohexylanyl, phenylglycyl or tyrosyl group, and Y represents a protonized arginyl or lysyl group, is disclosed. This substrate is useful for the quantitative determination of proteolytic enzymes of class E.C. 3.4.4., except thrombin and thrombin-like enzymes. |