发明名称 |
[1-Oxo-2-thienyl-2-substituted-5-indanyloxy (or thio)]alkanoic acids and derivatives thereof |
摘要 |
[1-Oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio)]alkaoic acid, derivatives thereof, their salts, esters and amides are disclosed. The products display a dual pharmaceutical utility in that they exhibit diuretic, saluretic and uricosuric activity. Also disclosed are processes for the preparation of such [1-oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio)]alkanoic acids, pharmaceutical compositions comprising therapeutically effective amounts of such compounds and methods of treatment comprising administering such compounds and compositions.
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申请公布号 |
US4177285(A) |
申请公布日期 |
1979.12.04 |
申请号 |
US19780889161 |
申请日期 |
1978.03.23 |
申请人 |
MERCK & CO INC |
发明人 |
CRAGOE, EDWARD J JR;WOLTERSDORF, OTTO W JR |
分类号 |
A61K31/495;A61K31/585;C07C45/67;C07C45/68;C07C45/71;C07C49/747;C07D241/26;C07D333/22;(IPC1-7):A61K31/12;C07D333/10 |
主分类号 |
A61K31/495 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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