发明名称 |
Method for the production of a vehicle substance which is capable of covalent bonding with biologically active matter |
摘要 |
Process for preparing a vehicle substance capable of covalent bonding with biological material, especially enzymes, by reacting a matrix containing -OH or NH2 groups with an organic diisocyanate under anhydrous conditions. The distance between the matrix and biological material may be extended by a stepwise reaction of the matrix with an organic diisocyanate, and organic spacer containing two or more -OH and/or NH2 groups and again with an organic diisocyanate. The coupling of the vehicle material with biological material takes place in buffered aqueous solution.
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申请公布号 |
US4177038(A) |
申请公布日期 |
1979.12.04 |
申请号 |
US19770797677 |
申请日期 |
1977.05.17 |
申请人 |
MAX-PLANCK-GESELLSCHAFT |
发明人 |
BIEBRICHER, CHRISTOF;LUCE, RUDIGER |
分类号 |
C08B37/00;C07K14/195;C07K14/41;C07K14/415;C07K14/81;C07K17/12;C08B15/06;C08F8/30;C08G18/38;C08G18/62;C08G18/64;C12N11/06;C12N11/12;(IPC1-7):D06M13/42;C08B37/02 |
主分类号 |
C08B37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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