摘要 |
Disclosed are novel 7-substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines of the general formula I <CHEM> wherein X is chloro, bromo or trifluoromethyl, and the pharmaceutically acceptable acid addition salts thereof. The novel compounds may be prepared by methods known per se. Preferably the compounds are prepared by dealkylation of a corresponding 8-alkoxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzazepine at position 8. The novel compounds are useful as intermediates in the preparation of corresponding esters and carbamates and show neuroleptic, antidepressive and antiagressive activity. |