发明名称 |
HUMANIZED ANTIBODIES AGAINST WEST NILE VIRUS AND THERAPEUTIC AND PROPHYLACTIC USES THEREOF |
摘要 |
The present invention relates to compositions comprising humanized antibodies or fragments thereof that immunospecifically bind to one or more antigens of a flavivirus, particularly of West Nile Virus (WNV) and methods for preventing, treating or ameliorating symptoms associated with a flavivirus, particularly of West Nile Virus (WNV) infection utilizing said compositions. In particular, the present invention relates to methods for preventing, treating or ameliorating to a human subject an effective amount of one or more humanized antibodies or fragments thereof that immunospecifically bind to a WNV antigen. The present invention also relates to detectable or diagnostic compositions comprising humanized antibodies or fragments thereof that immunospecifically bind to a WNV antigen and methods for detecting or diagnosing WNV infection utilizing said compositions.
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申请公布号 |
WO2006031825(A3) |
申请公布日期 |
2006.09.08 |
申请号 |
WO2005US32587 |
申请日期 |
2005.09.13 |
申请人 |
MACROGENICS, INC.;JOHNSON, LESLIE, S.;HUANG, LING |
发明人 |
JOHNSON, LESLIE, S.;HUANG, LING |
分类号 |
C12Q1/70 |
主分类号 |
C12Q1/70 |
代理机构 |
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