| 发明名称 |
RECOMBINANT ANTIBODY AND IMMUNOCONJUGATE TARGETED TO CD22-BEARING CELL AND TUMOR |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a recombinant antibody and an immunoconjugate targeted to CD22-bearing cells and tumors having high binding affinity and cytotoxic property. <P>SOLUTION: By this invention, is provided a recombinant antibody and an immunoconjugated body including a therapeutic agent or a detectable labeled peptide bonded to the recombinant anti-CD22 antibody having the V<SB>H</SB>including cysteine on the 44 amino acid position, and the V<SB>L</SB>including cysteine on the 100 amino acid position. <P>COPYRIGHT: (C)2008,JPO&INPIT |
| 申请公布号 |
JP2008208131(A) |
申请公布日期 |
2008.09.11 |
| 申请号 |
JP20080070484 |
申请日期 |
2008.03.18 |
| 申请人 |
USA GOVERNMENT |
发明人 |
FITZGERALD DAVID;PASTAN IRA;MANSFIELD ELIZABETH;KREITMAN ROBERT |
| 分类号 |
C07K19/00;G01N33/53;A61K38/00;A61K39/395;A61K45/00;A61K47/48;A61K48/00;A61P35/00;A61P35/02;C07K14/21;C07K16/28;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/08;G01N33/574 |
主分类号 |
C07K19/00 |
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