| 摘要 |
Herein is disclosed the utility of discontinuous regions of Extraceullar Matrix Proteins (ECM) in promoting cell growth in a Mesh. When the described scaffolds are applied on top of inert materials, cell in-growth is promoted and the attachment of the mesh is properly secured. In one aspect, the mesh has a side with reduced cellular in-growth and a side with enhanced in-grow th. Combining inert materials with cell attractive materials such as ECM can do this. This is particularly advantageous for use as hernia implant. Here, the mesh should adhere only to the abdominal wall (on one side of the mesh) without adhering to the intestines. In one aspect of the invention, the ine rt material is elongated and coated on both ends. This is particularly advan tageous for use as slings. Here, the mesh will adhere to the anchorage point s in the ends of the sling, and still allow urethral redistribution as a con sequence of bladder emptying.
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