| 发明名称 |
4-Iodomethylazetidin-2-one |
| 摘要 |
Disclosed is a process for preparing 7-(1-hydroxethyl)-3-(2-aminoethylthio)-1-carbadethiaceph-3-em-3-carbox ylic acid and its pharmaceutically acceptable salts and esters (I) by total synthesis starting with L-aspartic acid and proceeding via intermediates II and IIa (4-iodomethylazetidin-2-one): <IMAGE> I <IMAGE> II +TR <IMAGE> IIa
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| 申请公布号 |
US4174316(A) |
申请公布日期 |
1979.11.13 |
| 申请号 |
US19780933323 |
申请日期 |
1978.08.14 |
| 申请人 |
MERCK & CO INC |
发明人 |
CHRISTENSEN, BURTON G;RATCLIFFE, RONALD W;SALZMANN, THOMAS N |
| 分类号 |
C07D477/00;C07D205/08;C07D463/00;C07D477/04;C07D477/20;C07F7/10;(IPC1-7):C07D205/08 |
主分类号 |
C07D477/00 |
| 代理机构 |
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