摘要 |
New and useful phenylalkylcarbohydroxamic acids are disclosed of the formula <IMAGE> wherein: (a) R is selected from the group consisting of alkoxy of one to six carbon atoms, alkenyloxy of two to six carbon atoms, alkyl of one to six carbon atoms, and benzyloxy; (b) R1 and R2 are each selected from the group consisting of hydrogen, alkoxy of one to six carbon atoms, alkenyloxy of two to six carbon atoms, alkyl from one to six carbon atoms, and benzyloxy; (c) R3 and R4 are selected from the group consisting of hydrogen or alkyl of one to six carbon atoms; (d) R5 is hydrogen or R5 together with R3 or R4 represent methylene; and (e) n signifies the number 0 to 1, and non-toxic salts thereof, which novel compounds exert a pronounced inhibition of blood platelet aggregation and accelerate the disaggregation of platelet aggregates already formed.
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