| 摘要 |
5-Phenyl-2,4-pentadien-1-amines and salts thereof are provided having the structure <IMAGE> wherein R1 is hydrogen, lower alkyl, lower alkoxy, hydroxy, lower alkanoyloxy, nitro, cyano, amino, carboxy or lower alkoxycarbonyl, and R2 and R3 are the same or different and are hydrogen, lower alkyl, alkenyl-lower alkyl, aralkyl, and substituted lower alkyl. These compounds possess useful pharmceutical activites due to their ability to inhibit the prostaglandin-inactivating enzyme 15- alpha -hydroxyprostaglandin dehydrogenase.
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