发明名称 |
Method for preparing recombinant antigen complex using rotavirus nanoparticle |
摘要 |
Disclosed are a construct for expressing a rotavirus antigen complex loaded with a heterologous virus epitope, a vaccine composition containing the rotavirus antigen complex, a virus-like particle of rotavirus containing the rotavirus antigen complex, and a vaccine composition containing the virus-like particle of rotavirus. According to the present disclosure, an antigen complex containing a rotavirus antigen as well as a heterologous virus epitope and a virus-like particle of rotavirus containing the antigen complex can be produced in large scale at low cost. Thus, the present disclosure may be applied for research and development of novel complex vaccines for rotavirus and heterologous virus. |
申请公布号 |
EP2382989(B1) |
申请公布日期 |
2016.06.29 |
申请号 |
EP20110163914 |
申请日期 |
2011.04.27 |
申请人 |
CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMY COOPERATIONFOUNDATION |
发明人 |
KIM, WON YONG;CHUNG, IN SIK;KIM, JONG-BUM;SHON, DONG-HWA;THAN, VAN THAI;YOON, JANG WON;PARK, JOO HYOUNG;BAEK, IN-HYUK |
分类号 |
A61K39/29;A61K39/15;C07K14/10;C07K14/14 |
主分类号 |
A61K39/29 |
代理机构 |
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