发明名称 Naphthalene-tris-sulphonyl:imino:benzene derivs. - useful as complement inhibitors
摘要 <p>Naphthalenetris(sulphonyliminobenzene) derivs. of formula (I) are new: (where R is H or SO3A; and A is a cation; provided that each Ph ring contains 1 or 2 SO3A gps.). Complement inhibitors and so useful in affecting inflammation, coagulation, fibrinolysis, antibody-antigen reactions and other metabolic processes. Dose is 5-100 mg./lg. daily. In an example, 5,5',5"-(1,3,6-naphthalene-tris(sulphonylimino))tris-1,3-benzened- isulphonic acid Na salt was obtd.</p>
申请公布号 DE2817840(A1) 申请公布日期 1979.10.31
申请号 DE19782817840 申请日期 1978.04.24
申请人 AMERICAN CYANAMID CO. 发明人 BROWN CONROW,RANSOM;BERNSTEIN,SEYMOUR
分类号 A61K31/18;C07C311/15;(IPC1-7):C07C143/78 主分类号 A61K31/18
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