发明名称 |
FURO-3-CARBOXAMIDE DERIVATIVES AND METHODS OF USE |
摘要 |
Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein R1, Z1, Z2, and n are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by Tropomysin receptor kinases (Trk). Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions. |
申请公布号 |
SG11201605915W(A) |
申请公布日期 |
2016.08.30 |
申请号 |
SG11201605915W |
申请日期 |
2015.01.22 |
申请人 |
ABBVIE INC. |
发明人 |
ALTENBACH, ROBERT;LIU, HUAQING;CLAPHAM, BRUCE;AGUIRRE, ANA;COWART, MARLON;KOENIG, JOHN;SARRIS, KATERINA;SCANIO, MARC;SWINGER, KERREN;VASUDEVAN, ANIL;VILLAMIL, CLARA;WOLLER, KEVIN |
分类号 |
C07D407/12;A61K31/343;A61K31/4355;A61K31/5025;A61P23/00;C07D491/048;C07D491/20 |
主分类号 |
C07D407/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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