发明名称 |
Pyrimidine to pyrimidine transformation process |
摘要 |
There is provided a novel process for pyrimidine to pyrimidine transformations by the displacement of the 1,2,3-portion of a pyrimidine by a 1,3-ambident nucleophile. The novel process requires that the 1 and 3 nitrogens of the pyrimidine moiety be substituted. The novel process makes available, inter alia, novel uracils, simple methods of radioisotopically labeling pyrimidine nuclei, a simple and inexpensive method of preparing the important antiviral and antileukemic material pseudoisocytidine and its new active analog 2'-deoxypseudoisocytidine.
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申请公布号 |
US4171429(A) |
申请公布日期 |
1979.10.16 |
申请号 |
US19770782353 |
申请日期 |
1977.03.29 |
申请人 |
RESEARCH CORP |
发明人 |
CHU, CHUNG K;FOX, JACK J;HIROTA, KOSAKU;REICHMAN, URI;WATANABE, KYOICHI A |
分类号 |
C07D239/46;C07D239/54;C07D239/56;C07H19/06;(IPC1-7):C07D239/46;C07D407/04 |
主分类号 |
C07D239/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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