发明名称 |
SUPPRESSION OF THROMBOCYTE AGGREGATION |
摘要 |
<p>2-(4,5-bis-p-chlorophenyloxazol-2-yl-mercapto)-propionic acid and its physiologically acceptable salts in the form of an admixture with acetylsalicylic acid or a physiologically acceptable salt thereof is useful for suppressing aggregation of thrombocytes, particularly when administered in a mole ratio of the acetylsalicylic acid to the priopionic acid derivative of 60:1 to 0.1:1. This is useful especially in humans, e.g. for prophylaxis and therapy in cases involving risk of arterial or venous thrombosis.</p> |
申请公布号 |
CA1063939(A) |
申请公布日期 |
1979.10.09 |
申请号 |
CA19760265049 |
申请日期 |
1976.11.05 |
申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG |
发明人 |
LEOPOLD, GOTZ;LISSNER, REINHARD;MAISENBACHER, JURGEN;MEHRHOF, WERNER;GANTE, JOACHIM |
分类号 |
C07D263/16;A61K31/42;A61K31/421;A61P7/02;(IPC1-7):61K31/42 |
主分类号 |
C07D263/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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