| 摘要 |
<p>The present invention provides a process for the synthesis of a 1,4-diaza-2-cycloalkanone characterized in that a diamine of the formula <CHEM> wherein R1 and R2 are independently selected from hydrogen, halogen, alkyl of 1 to 12 carbon atoms, hydroxyalkyl, haloalkyl, cyanoalkyl, aminoalkyl, iminoalkyl, ether, nitrosyl, hydroxyalkyl ethers, cyano alkyl ethers, alkenyl, alkaline and carboalkoxy: R3 to R6 being independently selected from alkyl of 1 to 12 carbon atoms, cycloalkyl, hydroxycycloalkyl, aminoalkyl, iminoalkyl, alkenyl, aralkyl and alkylene, provided further that any two of the above hydrocarbon substituents pendant from the same carbon atoms can collectively form a cyclic or alicyclic hydrocarbon and n is 0 to 3 is contracted in the presence of a phase transfer catayst, with a stoichiometric excess of an Ê-trihaloalkyl-alcohol of the formula <CHEM> wherein R7 and R8 are selected from the same group of substituents as R3 to R6 X is halogen; and m is a number from 0 to 5.</p> |
