摘要 |
<p>Penicillin derivs. and its nontoxic salts (I; R = furyl, thienyl, cycloalkyl, cycloalkenyl, phenyl, hydroxy, halogen, nitro, low alkyl, low alkoxy, amino, or carboxyl group substituted phenyl; A,B = substituted 5-or 6-membered residual group), useful as antibiotic, were prepd. by reaction of compd. (II; Rx = H, or ester or carboxyl protecting group which is able to hydrolysis in the organism) or its N-protected deriv. with N-acyl deriv.(III) and then elimination of the N-protected group by hydrolysis or alcoholysis.</p> |