1,2',3,6'-Tetra-N-acetyl-amino:glycoside derivs. prepn. - by reaction of N-de:acetyl derivs. with acetic anhydride, useful as antibacterial intermediates

摘要

In the prodn. of N-acetyl-aminoglycoside derivs. of formula (I), corresponding N-deacetyl cpds. of formula (II) are reacted with acetic anhydride. (where R1, R2 = H or CH3; R3 = is not 2C alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, cycloalkylalkyl, cycloalkenylalkyl, aryl or aralkyl; X = H or X+X = additional C-C bond; and Y = (I) are useful as intermediates for antibacterially active aminoglycoside derivs.