EXTRACTS OF THE HAEMOPOIETIC SYSTEM

摘要

Highly purified granulocytic chalone and a process for the semi-continuous processing of whole blood to provide extracts of the haemopoietic chalones, erythrocytic lymphocytic and granulocytic chalones. By means of a continuous lysis unit the red blood cells are preferentially and substantially completely lysed while leaving unaffected the leucocytes which are then separated from the red cell debris by means of a centrifuge in which the intact leucocytes attach to the rotor. The intact leucocytes are extracted and the extract subjected to ultrafiltration to provide extracts of the haemopoietic chalones, which may be further isolated and purified. A pharmaceutical composition comprising a chalone for use in the treatment of patients suffering from myeloid leukaemia. Granulocytic chalone extracts obtained in the extraction procedure described may be used in the pharmaceutical composition.