摘要 |
<p>N-Alkylated-8-aminated-2,6-methano-3-benzazocines,, useful as strong analgesics, are prepared by one route comprising reduction of 8-nitro intermediates or by another route comprising Birch type reduction of 8-methoxy intermediates followed by dehydration-rearrangement of the oximes of the resulting 8-oxo intermediates.</p> |