| 摘要 |
<p>Described herein are novel hydroxylpolyhaloisopropylsubstituted ureido compounds exhibiting useful antihypertensive activity, processes for their preparation and pharmaceutical compositions containing these compounds. The ureido-compounds are selected from phenyl ureas, oxazolines and quinazolines represented by the formula: and the pharmaceutically acceptable salts of the oxazolines and quinazolines, where Z represents , or, together with X2, the grouping in which R1 is ethylene or substituted ethylene and R and R2 represent other specified substituents and wherein one of X2 and X4 is the hydroxypolyhaloisopropyl grouping in which Y independently represents hydrogen chlorine or fluorine while the other of X2 and X4, as well as X3, X5 and X6, represent other specified substituents.</p> |
