发明名称 |
L'-SUBSTITUTED AMINO-2-ALKYL-5-HYDROXY-7, 8-CYCLOPENTANO (H)-1, 2,-TETRAHYDROISOQUINOLINES |
摘要 |
<p>2-Alkyl-7,8-cyclopentanoh!-1,2,3,4 tetrahydroisoquinolines of the formula wherein R is an aryl-lower alkyl amino group, an aryl-lower alkyl imino group, a diaryl-lower alkyl amino group or a diaryl-lower alkyl imino group, R1 is hydrogen or a lower alkyl-group and R2 is a lower alkyl group, and acid addition salts and quaternary ammonium salts thereof, and the use of such compounds in pharmaceutical compositions to lower blood pressure in hypertensive animals.</p> |
申请公布号 |
CA1063116(A) |
申请公布日期 |
1979.09.25 |
申请号 |
CA19750223270 |
申请日期 |
1975.03.27 |
申请人 |
MARION LABORATORIES, INC. |
发明人 |
MATHISON, IAN W.;SOLOMONS, WILLIAM E.;JONES, RAYMOND H. |
分类号 |
A61K31/47;A61K31/473;A61P9/12;C07D217/04;C07D221/16;(IPC1-7):07D221/16 |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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