| 摘要 |
PURPOSE:To prepare a carcinostatic agent for oral administration having high absorbability, excellent remedying effect, and low side effects, by dissolving or dispersing a carcinostatic agent in a specific base such as glycerine fatty acid ester, etc. CONSTITUTION:A carcinostatic agent such as 5-fluorouracil, cytosine arabinoside, etc., is dissolved or dispersed in a base such as glycerine fatty acid ester (e.g. dioctyldecyl glyceride), an edible oil, a fatty acid (e.g. linolic acid), a fatty acid ester (e.g. propyl myristate), an oleovitamin (e.g. vitamin A), a phospholipid (e.g. ovolecithin), chlolic acid or its salt, to obtain the objective carcinostatic agent for oral administration. The original carcinostatic agent may be dispersed or dissolved in water, polyethylene glycol, etc., before dispersing in the base, or may be micro-encapsulated with the base. |
