发明名称 |
PIPERIDINOALKYL DERIVATIVES OF PURINES |
摘要 |
<p>New piperidinoalkyl derivatives of purine and their process of preparation are provided of formula (I) (I) wherein R1 is a hydrogen atom or a lower alkyl radical, R2 is a hydrogen atom, a lower alkyl radical, a hydroxy-lower-alkyl radical or a cycloalkyl radical or R1 and R2, together with the nitrogen atom to which they are attached, form a heterocyclic ring, and R3 is a hydrogen or halogen atom or a lower alkyl or lower alkoxy radical; and the acid addition salts thereof with pharmacologically compatible acids; the new derivatives suppress the liberation and action of histamine; they also possess an anti-hypertensive action.</p> |
申请公布号 |
CA1062708(A) |
申请公布日期 |
1979.09.18 |
申请号 |
CA19760264609 |
申请日期 |
1976.10.28 |
申请人 |
BOEHRINGER MANNHEIM G.M.B.H. |
发明人 |
FRIEBE, WALTER-GUNAR;THIEL, MAX;STACH, KURT K. G.;WILHELMS, OTTO-HENNING;VON MOELLENDORFF, ERIKA;SPONER, GISBERT |
分类号 |
A61K31/52;A61P3/00;A61P9/12;A61P29/00;A61P37/08;C07D401/06;C07D401/14;C07D473/34;(IPC1-7):07D473/34 |
主分类号 |
A61K31/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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