发明名称 |
4-Alkyl-alkanoyl-7-hydroxy-coumarin prepn. in good yield - by alkanoylating corresp. unsubstituted cpd. using Friedel-Crafts catalyst |
摘要 |
<p>4-Alkyl-6 (or 8)-alkanoyl-7-hydroxycoumarins of formula (I):- (where R is unsubstd. alkyl; and R1 is alkanoyl ortho to the 7-OH) are prepd. by reacting a corresp. 4-alkyl-7-hydroxycoumarin (II) with an alkanoylating agent in presence of a Friedel-crafts catalyst. Good yields of (I) in a simple process compared with the previously used Fries rearrangement; (I) are intermediates for pharmacologically active cpds.</p> |
申请公布号 |
DE2810522(A1) |
申请公布日期 |
1979.09.13 |
申请号 |
DE19782810522 |
申请日期 |
1978.03.10 |
申请人 |
FISONS LTD. |
发明人 |
TOWNEND,JOHN;HAZARD,RICHARD |
分类号 |
C07D311/16;(IPC1-7):C07D311/16 |
主分类号 |
C07D311/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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