发明名称 |
2-Methyl-6-alkyl-11-aminoalkyl-6,11-dihydro-5H-pyrido(2,3-B)(1,5)benzodiazepin-5-ones and salts thereof |
摘要 |
Compounds of the formula <IMAGE> wherein R1-is hydrogen, alkyl of 1 to 6 carbon atoms or benzyl; R2-is alkyl of 1 to 6 carbon atoms, cycloalkyl of 5 to 7 carbon atoms or, together with R1 and the adjacent nitrogen atom, pyrrolidino, piperidino, hexamethyleneimino, morpholino or N'-methyl-piperazino, where each of the heterocycles may have one or two alkyl of 1 to 3 carbon atoms or one or two methoxy substituents attached thereto; R3,-R4 and R5 are each hydrogen or methyl; R6-is alkyl of 1 to 4 carbon atoms; and A-is alkylene of 2 to 4 carbon atoms; AND NON-TOXIC, PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF; THE COMPOUNDS AS WELL AS THEIR SALTS ARE USEFUL AS BRONCHOSPASMOLYTICS AND BRONCHOSECRETOLYTICS.
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申请公布号 |
US4167570(A) |
申请公布日期 |
1979.09.11 |
申请号 |
US19770837578 |
申请日期 |
1977.09.28 |
申请人 |
BOEHRINGER INGELHEIM GMBH |
发明人 |
SCHMIDT, GUNTHER;PUSCHMANN, SIGFRID;ENGELHARDT, GUNTHER |
分类号 |
A61K31/55;A61K31/551;A61P11/08;A61P11/10;C07D213/80;C07D471/04;(IPC1-7):A61K31/55 |
主分类号 |
A61K31/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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