摘要 |
This invention relates to novel dermatologically active androstadienes of the formula …<CHEM>… wherein M is a benzyl, phenethyl, methylbenzyl, dimethylbenzyl, chlorobenzyl or dichlorobenzyl group or an alkyl group having from 1 to 8 carbon atoms,… X is a hydrogen or fluorine atom,… Y is an oxygen atom, or, provided that X is a hydrogen atom, Y can also be (H, H),… and n is 1 or 2,… to processes for their preparation, and to pharmaceutical compositions containing them; and also to related androstadienes useful as intermediates in their preparation. …<??>The novel compounds of the formula IA can be used in particular in the treatment of acne. |