VERFAHREN ZUR HERSTELLUNG VON N HOCH 2-ARYLSULFONYL-L-ARGININAMIDEN UND IHRER PHARMAZ5UTISCH VERTRAEGLICHEN SALZE
摘要
<p>The arginamides correspond to the formula: <IMAGE> in which Ar represents various aromatic groups and R represents one of the following groups: <IMAGE> The detailed definition of the Ar groups and the symbols in the R groups is found in Claim 1. The compounds and their acid addition salts are prepared from L-arginine by a three-step process. They have a specific inhibitory action against thrombin and can be used, preferably in the form of pharmaceutical preparations, for the treatment and for the prophylaxis of thromboses.</p>
申请公布号
DD137352(A5)
申请公布日期
1979.08.29
申请号
DD19780203302
申请日期
1978.01.19
申请人
MITSUBISHI CHEMICAL INDUSTRIES LTD,JP;SHOSUKE OKAMOTO,JP