| 发明名称 |
Pyrimidones, processes for their preparation and pharmaceutical compositions containing them. |
| 摘要 |
<p>Pyrimidones which are histamine H<Sub>2</Sub>-antagonists have the structure
<Chemistry id="chema01" num="0001"><Image id="ia01" he="21" wi="61" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>in which D is hydrogen or an aminoalkyl group, X is oxygen or sulphur, Y is oxygen, sulphur or methylene, n is 2 or 3, Z is hydrogen or lower alkyl, A is Ci-C5 alkylene in which one methylene group can be replaced by oxygen or sulphur, and B is hydrogen, methyl, C<Sub>3</Sub>-C<Sub>6</Sub> cycloalkyl, or an aryl or heteroaryl group.</p> |
| 申请公布号 |
EP0003677(A2) |
申请公布日期 |
1979.08.22 |
| 申请号 |
EP19790300190 |
申请日期 |
1979.02.07 |
| 申请人 |
SMITH KLINE & FRENCH LABORATORIES LIMITED |
发明人 |
BROWN, THOMAS HENRY;IFE, ROBERT JOHN |
| 分类号 |
C07D409/14;A61K31/495;A61K31/513;A61P1/04;A61P1/14;A61P9/12;A61P29/00;A61P43/00;C07D213/40;C07D213/55;C07D213/61;C07D213/64;C07D213/85;C07D239/56;C07D317/46;C07D333/18;C07D333/20;C07D405/12;C07D405/14;C07D409/12;(IPC1-7):07D405/00;61K31/505;07D409/00 |
主分类号 |
C07D409/14 |
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