发明名称 CYCLOPENTANE DERIVATIVES
摘要 <p>Cyclopentane derivatives of the general formula wherein R is hydrogen or lower alkyl; R1 is hydrogen, lower alkyl, carboxy, lower alkoxycarbonyl, hydroxymethyl, lower alkoxymethyl or the group ; R2 is hydroxy and R3 is hydrogen or R2 and R3 together form and oxo group; R4 is hydrogen, lower alkyl or fluoro, R5 is hydrogen or lower alkyl; and the dotted bond can be hydrogenated; with the proviso that when R4 and R5 are both hydrogen, R1 is lower alkoxycarbonyl, hydroxymethyl, lower alkoxymethyl or the group , and enantiomers and racemates thereof. The compounds are therapeutically active.</p>
申请公布号 CA1060888(A) 申请公布日期 1979.08.21
申请号 CA19740206171 申请日期 1974.08.02
申请人 HOFFMANN-LA ROCHE LIMITED 发明人 HOLLAND, GEORGE W.;JERNOW, JANE L.;ROSEN, PERRY
分类号 A61K9/20;A61K31/19;A61K31/215;A61K31/557;A61K31/5575;A61P43/00;C07C;C07C23/08;C07C45/63;C07C45/67;C07C45/68;C07C53/21;C07C53/50;C07C67/00;C07C69/66;C07C69/74;C07C401/00;C07C405/00;C07D307/93;C07D307/935;C07D309/12;C07F9/143;C07F9/40;C07F9/50;C07F9/54;(IPC1-7):07C177/00 主分类号 A61K9/20
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