| 摘要 |
Alkylenediamine amides corresponding to the general formula (I) <IMAGE> (I) in which R1 and R2 each represent, independently of one another, a hydrogen atom, an alkyl having 1 to 4 carbon atoms or the benzyl radical, n is equal to 2, 3 or 4 and R represents either a cycloalkyl radical having 3 to 6 carbon atoms, or a radical <IMAGE> in which m is 0, 1 or 2, <IMAGE> <IMAGE> in which m is 0, 1 or 2 and p is 0, 1 or 2, and also their addition salts with pharmaceutically acceptable acids. These compounds may be prepared by reacting an aminoamide <IMAGE> (III) with a 4-amino-2-halogeno-6,7-dimethoxyquinazoline (II). The compounds are useful in treating cardiovascular disorders, and pharmaceutical compositions containing the compounds are also claimed. |
