发明名称 |
PROCEDE POUR OBTENIR DES DERIVES D'ACIDE CEPHALOSPORANIQUE |
摘要 |
<p>1460916 Preparation of cephalosporin derivatives BRISTOL-MYERS CO 21 Dec 1973 [26 Dec 1972] 23368/76 Divided out of 1460914 Heading C2C The compound I having the D-(-)-configuration in the 7-side chain and salts and esters thereof are prepared by reacting a compound II fully protected by easily cleavable silyl groups with an acylating derivative of an acid III in which B is an amino-protecting group, followed by removal of the protecting groups and optional esterification or salt formation. Pharmaceutical compositions used as antibiotics contain a compound I when prepared by the above process, together with a suitable carrier or diluent.</p> |
申请公布号 |
RO66051(A) |
申请公布日期 |
1979.08.15 |
申请号 |
RO19740077301 |
申请日期 |
1974.01.16 |
申请人 |
BRISTOL MYERS CO,US |
发明人 |
WILLNER,DAVID,US;CRAST,LEONARD,US |
分类号 |
C07C227/12;A61K31/545;A61K31/546;A61P31/04;C07C67/00;C07C227/00;C07C227/14;C07C229/36;C07D285/06;C07D501/06;C07D501/36;(IPC1-7):C07D501/60 |
主分类号 |
C07C227/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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