发明名称 Heterocyclylcarbonyl derivatives of urea, agents for dissolution of gallstones
摘要 {PG,1 Heterocyclylcarbonyl derivatives of urea having the formula {r1 {tc,1 {rb R{AB,4 {M,1 {AD,0 O{MR,1 C{AB,4 NH{AB,4 {M,1 {AD,0 O{MR,1 C{AB,4 N{M,1 {AB,2 R{HD 1{MR,1 {AB,6 R{HD 2{RE {PS {PS wherein R is a heterocyclyl group; R{HD 1 {L is hydrogen, alkyl having up to ten carbon atoms or phenyl; R{HD 2 {L is R{HD 1{L , 1-naphthyl and phenylalkyl having 1 to 4 carbon atoms in the alkyl group; and R{HD 1 {L and R{HD 2 {L when taken together with the nitrogen to which they are attached are morpholino, thiomorpholino or a 6{14 8 membered nitrogen containing heterocyclic ring; methods for their preparation and use as agents for dissolving gallstones.
申请公布号 US4163784(A) 申请公布日期 1979.08.07
申请号 US19780884858 申请日期 1978.03.09
申请人 PFIZER INC 发明人 HOLLAND, GERALD F
分类号 C07D275/02;A61K31/44;A61K31/4406;A61K31/4427;A61K31/443;A61K31/455;A61P1/16;C07D213/81;C07D213/82;C07D215/54;C07D261/18;C07D263/34;C07D275/03;C07D275/04;C07D277/20;C07D277/56;C07D285/06;C07D285/10;C07D307/68;C07D401/12;C07D405/12;C07D413/12;(IPC1-7):A61K31/54;A61K31/53 主分类号 C07D275/02
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