摘要 |
{PG,1 Heterocyclylcarbonyl derivatives of urea having the formula {r1 {tc,1 {rb R{AB,4 {M,1 {AD,0 O{MR,1 C{AB,4 NH{AB,4 {M,1 {AD,0 O{MR,1 C{AB,4 N{M,1 {AB,2 R{HD 1{MR,1 {AB,6 R{HD 2{RE {PS {PS wherein R is a heterocyclyl group; R{HD 1 {L is hydrogen, alkyl having up to ten carbon atoms or phenyl; R{HD 2 {L is R{HD 1{L , 1-naphthyl and phenylalkyl having 1 to 4 carbon atoms in the alkyl group; and R{HD 1 {L and R{HD 2 {L when taken together with the nitrogen to which they are attached are morpholino, thiomorpholino or a 6{14 8 membered nitrogen containing heterocyclic ring; methods for their preparation and use as agents for dissolving gallstones.
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