Azetidine compounds and process for production

摘要

Novel azetidine, and particularly 3-pyridyl-azetidine, compounds are disclosed. These compounds are produced from gamma -amino alcohols by a sequence comprising disulfonation to produce the sulfonamido-alkylsulfonate and then cyclization to the N-sulfonylazetidine. These azetidine compounds may then be transformed, as desired, to various N-derivatives by substitution of hydrogen or other univalent organic groups on the secondary amine of the azetidine ring.