| 摘要 |
<p>A water-soluble, injectable cross-linked orgotein having a molecular weight of up to 500,000 is provided herein. The orgotein molecule is intermolecularly cross-linked by at least one organic bridging group with at least one molecule of a water-soluble, injectable non-antigenic protein. The organic bridging group is formed by the reaction of orgotein or a mixture of orgotein and another water-soluble, injectable non-antigenic protein, with an organic difunctional cross-linking agent. This novel cross-linked orgotein has a substantially longer half-life in the blood after injection than orgotein.</p> |
