摘要 |
This invention relates to certain structural and pharmacological analogs of prostacyclin (PGI2) wherein a nitrogen atom is substituted for the 6,9 alpha -epoxy-oxygen of prostacyclin. These novel nitrogen-containing prostacyclin-type compounds are useful for the pharmacological purposes for which prostacyclin is used, e.g., as antithrombotic agents, antihypertensive agents, antiasthma agents, nasal decongestants, or regulators of fertility and procreation.
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