发明名称 Treatment of animals with 2,6-bis(2-hydroxybenzyl)phenols to eradicate trematodes
摘要 A process for killing internal parasites of warm blooded animals which process comprises treating the infected animal with an effective amount of a composition comprising as active ingredient a compound of the general formula I: <IMAGE> I wherein R1, R2 and R3, which may be the same or different, are hydrogen, lower alkyl, lower alkenyl, lower alkanoyl, lower alkenoyl, aroyl or CH2COOR4 wherein R4 is hydrogen or lower alkyl; B, C and D, which may be the same or different, are halogen, optionally substituted lower alkyl, optionally substituted aryl, lower alkenyl, lower alkoxy, hydroxy, cyano, nitro, or COR5 wherein R5 is hydroxy, lower alkoxy or NR6R7 wherein R6 and R7, which may be the same or different, are hydrogen or lower alkyl; A, E, X, Y and Z, which may be the same or different, are hydrogen, halogen, optionally substituted lower alkyl, optionally substituted aryl, lower alkenyl, lower alkoxy, hydroxy, cyano, nitro, or COR5 wherein R5 is as hereinbefore defined; J and G, which may be the same or different, are hydrogen, lower alkyl, optionally substituted aryl, cyano, nitro or trichloromethyl or, together with the geminal hydrogen, the group =CCl2; or an optical isomer thereof; or a salt thereof; and wherein lower alkyl and lower alkoxy are defined as groups containing from 1 to 6 carbon atoms, lower alkenyl and lower alkanoyl are defined as groups containing from 2 to 6 carbon atoms and lower alkenoyl is defined as a group containing from 3 to 6 carbon atoms; and an inert carrier therefor.
申请公布号 US4163801(A) 申请公布日期 1979.08.07
申请号 US19770812471 申请日期 1977.07.05
申请人 ICI AUSTRALIA LTD 发明人 FORSYTH, BRUCE A;MCGARRY, ERROL J
分类号 A61K31/05;A61K31/055;A61K31/22;A61K31/275;C07C37/00;C07C37/055;C07C37/16;C07C37/18;C07C37/20;C07C37/62;C07C39/367;C07C41/16;C07C43/225;C07C45/54;C07C69/65;C07C205/26;(IPC1-7):A61K31/05;A61K31/27 主分类号 A61K31/05
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