发明名称 Hepatitis B surface antigen particle prepn. - by ammonium sulphate pptn., isopycnic banding and rate zonal banding
摘要 <p>Hepatitis B surfact antigen particles (I) are prepd. by treating a fluid from a suitable human donor with (NH4)2SO4 to precipitate an antigen fraction, and then subjecting this fraction to an isopycnic banding and to a rate zonal banding. (I) is recovered in the density rang 1.13-1.16 g./ml. Prepn. is a faster and more economical method for concentrating and purifying (I) obtd from plasma, saliva, faecal extract, nasal pharyngeal secretions, bile, spinal fluid, sweat, urine, semen, vagnal secretions or menstrual blood.</p>
申请公布号 NL7800952(A) 申请公布日期 1979.07.30
申请号 NL19780000952 申请日期 1978.01.26
申请人 MERCK & CO., INC. TE RAHWAY, NEW JERSEY, VER. ST. V. AM. 发明人
分类号 C07K14/02;(IPC1-7):61K39/12 主分类号 C07K14/02
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