摘要 |
<p>Benzyl pyrimidine derivatives of the formula: (I) wherein R1 and R2 each independently represent an amino, optionally C1-3-alkyl-substituted pyrrolo, -NHR3, -N(R3)2, -NHR4 or -N(R3)(R4) group, R3 represents a C1-4-alkyl group, R4 represents an acyl group, derived from a lower aliphatic carboxylic or sulphonic acid, and Z represents a hydrogen, chlorine or bromine atom, a piperidino group or a group R3, OR3 or -N(R3)2, and their salts, are disclosed as well as processes for their manufacture. The compounds(I) and their salts possess antibacterial activity.</p> |