Method for blocking allergic responses

摘要

A group of relatively low molecular weight polypeptides having from 3 to 10 amino acids block the allergic response. These "blocking" polypeptides have amino acid sequences corresponding to amino acid sequences appearing in the 2nd, 3rd and 4th domains of the epsilon chain of IgE. Certain derivatives of such polypeptides also exhibit "blocking" activity. Specific active "blocking" polypeptides are disclosed and the synthesis and use thereof are described.