发明名称 Levulinic acid salt
摘要 The invention concerns a levulinic acid addition salt of the antihypertensive agent 4-amino-6,7-dimethoxy-2-[4-(5-methylthio-1,3,4-oxadiazole-2-carbonyl]p iperazin-1-yl)quinazoline in which the base to acid mole ratio is 1 to from 1.25-1.35. The salt is characterized in having improved water solubility and stability compared to the levulinate salt having a 1:1 ratio of base to acid.
申请公布号 US4161595(A) 申请公布日期 1979.07.17
申请号 US19780947678 申请日期 1978.10.02
申请人 BRISTOL-MYERS 发明人 GRANATEK, ALPHONSE P;KAPLAN, MURRAY A
分类号 C07C59/185;(IPC1-7):C07D239/95 主分类号 C07C59/185
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