发明名称 BIGUANIDES, PROCESS FOR THEIR PREPARATION AND APPLICATIONS THEREOF
摘要 <p>The present invention relates to compounds having the general formula: (I) in which n1 and R2, which may be the same or different, represent each a hydrogen atom, a C1-C6 alkyl radical or a C3-C6 cycloalkyl radical; R3 represents a hydrogen atom or a C1-C4 alkyl radical; R4 and R5, which may be the same or different, represent a hydrogen atom, a C1-C6 alkyl radical or, together with the nitrogen atom to which they are attached, form a pyrrolidino, piperidino, morpholino or piperazinyl radical optionally substituted with a C1-C4 alkyl radical, or a 4-hydroxy-piperidino radical, and their pharmaceutically acceptable acid eddition salts. Said compounds are therapeutically useful for the control of the cardio-vascular system and of the blood pressure.</p>
申请公布号 CA1058616(A) 申请公布日期 1979.07.17
申请号 CA19760243550 申请日期 1976.01.13
申请人 SOCIETE NOUVELLE D'EXPLOITATION DES LABORATOIRES ARON 发明人 STERNE, JEAN-JACQUES
分类号 C07D261/14;(IPC1-7):07D413/12 主分类号 C07D261/14
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