发明名称 Verfahren zur Herstellung loeslicher Adrenochrom-Zubereitungen
摘要 Aqueous solutions of adrenochrome monoxime and semicarbazone comprise a compound of general formula <FORM:0914039/VI/1> wherein R represents a formyl, acetyl, propionyl, butyryl, aminoacetyl, phenylacetyl, benzoyl or salicylye radical, and Y represents a hydrogen atom, an allkal or alkaline earth metal, ammonium, an organically substituted ammonium, amino or amido radical as solubilizing agent and which is preferably present in an amount by weight of forty times that of the adrenochrome derivative. Specified compounds of the above general formula are: N - acetyl - 1 - naphthylamine - 4 - sodium sulphonate and the corresponding N-butyryl compound. The solutions may be dried, e.g. by evaporation or spray drying under vacuum to give solid compositions. Local an sthetics, e.g. dibucaine hydrochloride may also be present.
申请公布号 DE1289619(B) 申请公布日期 1969.02.20
申请号 DE1959R025762 申请日期 1959.06.18
申请人 GARRIGA, RAMON RIUS 发明人
分类号 A61K31/40;A61K31/63 主分类号 A61K31/40
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