| 摘要 |
1444879 Tetrahydropyridine compounds BAYER AG 7 Feb 1975 [9 Feb 1974] 5313/75 Heading C2C The invention comprises compounds of formula wherein R 1 is alkyl or alkenyl, possibly containing 1-2 O atoms in the chain; R 2 is an acyclic or alicyclic hydrocarbon radical, or is Ph (possibly substituted), or naphthyl, quinolyl, isoquinolyl, pyridyl, pyrimidyl, thenyl or furyl; and R 3 is alkyl or possibly substituted Ph. These compounds are prepared by reacting in an inert organic solvent at 20-200‹ C. a 4-R 2 CH=-2-R 3 -oxazolin-5-one with Therapeutic compositions for oral, parenteral or rectal administration comprise the above compounds, which have coronarydilatory, antihypertensive, antifibrillation, vascular-spasmolytic and muscular-spasmolytic activity and also influence the blood cholesterol and lipid levels. |
