发明名称 Process for the separation of antibiotic macrolides
摘要 This case relates to a novel process which aids in the isolation and purification of novel compounds which are produced by the microorganism, Streptomyces avermitilis. The process described herein utilizes a hydroxypropyl Sephadex column chromatographic step in the isolation of the compounds from broth. The compounds which are isolated and purified are described generically s C-076 and have significant parasiticidal activity.
申请公布号 US4160083(A) 申请公布日期 1979.07.03
申请号 US19770838710 申请日期 1977.10.03
申请人 MERCK & CO., INC. 发明人 COLE, LUCILLE J.
分类号 C07H19/01;(IPC1-7):C07H17/08 主分类号 C07H19/01
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