发明名称 NAPHTHALENE DERIVATIVE AND MANUFACTURE
摘要 Compounds corresponding to the formula <IMAGE> (I) in which R' is a hydrogen atom or a methyl radical and R represents a radical <IMAGE> in which Z is O, S, S->O, SO2 or NR1, in which R1 is a hydrogen atom or an alkyl, CONR2R3, COOR2, COR2 or SO2R2 radical, R2 and R3 each representing, independently of one another, a hydrogen atom, an alkyl radical having 1 to 4 carbon atoms, a phenyl radical or a CF3 radical, in the form of racemates or enantiomers if R' is CH3, and also, where appropriate, their addition salts with pharmaceutically acceptable acids. The compounds and salts are useful as anti-inflammatory agents, e.g. for treatment of arthritis. A process for preparing them and pharmaceutical compositions containing them are also claimed.
申请公布号 JPS5481280(A) 申请公布日期 1979.06.28
申请号 JP19780145934 申请日期 1978.11.24
申请人 SYNTHELABO 发明人 TOOMASU ANDORIYUU PAASERU;BURAHAMU SHIYURUUTO;DANIERU JIYAN MARII KARUTEIE
分类号 C07D295/08;A61K31/495;A61K31/535;A61K31/5375;A61K31/54;A61P29/00;C07D295/096;C07D295/18;C07D295/185;C07D295/192;C07D295/20;C07D295/205;C07D295/215;C07D295/22;C07D295/26 主分类号 C07D295/08
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