摘要 |
What is disclosed are medicinal compositions, useful as anti-depressive agents, containing a compound of the formula; <IMAGE> (I) in which R1, R3 and R4, which may be identical or different, and represent hydrogen atoms or lower alkyl or aralkyl groups, and R2 and R2', which may be identical or different, represent hydrogen or halogen atoms, hydroxy or trifluoromethyl groups or lower alkyl, alkoxy or aralkoxy groups, it also being possible that two adjacent radicals form an alkylene-dioxy radical, and R5 represents a hydrogen or halogen atom, a hydroxy, trifluoromethyl or nitro group or a lower alkyl, alkoxy or aralkoxy radical, and their salts with acids (active substance A) together with 7-chloro-1-methyl-5-phenyl-1H-1,5-benzodiazepine-2,4 (3H,5H)-dione (active substance B), and their use as antidepressive agent. |